The Nnabagereka, in collaboration with the Ministry of Health, is carrying out a program on advocacy and social mobilization to increase demand and utilization for immunization and safe motherhood services in Buganda in particular, and Uganda in general. The Nnabagereka is also working with international organizations such as the United Nations Fund for Population activities to contribute to increased commitment of cultural, religious, community and clan leaders, policy and decision-makers on matters of the girl-child, gender issues, adolescent reproductive, HIV/AIDS and manageable family size.

Through the Heart Foundation Fund Raising Concert that was sponsored by MTN, Her Royal Highness helped to raise over 20 million Uganda shillings towards acquiring a heart equipment to treat heart patients at Mulago Hospital in 2006.